Why Molecular Hydrogen is Important?

About 150 years ago, molecular hydrogen (H2) had been identified as the main component of intestinal gas in humans, with subsequent studies detailed its production by coliform bacteria of the large intestine as a consequence of food fermentation. Being traditionally recognized as a biologically inert gas, endogenous H2 is either passed in flatus or absorbed by colon mucosa into the circulation and then released by the respiration outside the body. However, recent studies suggest that endogenous H2 has an associative effect in the human body, acting as an anti-inflammatory biomolecule that manifests cardioprotective effects or safeguards against tissue injury. So begins the story.

Research into therapeutic uses of molecular Hydrogen started in earnest in 2007 with a paper by Ikuroh Ohsawa titled “Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals” (G). Ohsawa found H2 selectively reduced toxic hydroxyl radicals in the Reactive Oxygen Species (ROS). Its action effectively protected cells, but more significantly, H2 did not react with other ROS that possess physiological roles such as cell signaling. The word “selectively” started the “Hydrogen Rush” of 2007.  

The toxic hydroxyl radical ROS produces oxidative stress in the cell, capable of disrupting cell activity or destroying the cell. Cell mitochondria are responsible for much of this stress. Mitochondria are organelles (lightly translated as cell organs) within a cell that manufacture the cell’s fuel – ATP. Mitochondria were once single-cell bacteria attached to the outside of a cell. The tik-tok of the evolutional trail begins with each needing the other to survive. The cell, intent on protecting the mitochondria, invites them inside and locks the door. The mitochondria produce waste needing disposal, and being inside the cell, its highly reactive waste is deposited in the cell’s body. 

What is Oxidative Stress – The Movie

Practically every condition, disease, or injury has an association with ROS production. The mechanics of both the reactive and signaling ROS is understood relatively well. The Molecular Hydrogen Rush of 2007 provided researchers with a tool to selectively manipulate ROS and observe the results. Hydrogen was quickly recognized to be effective in treating a wide range of conditions and diseases. Hydrogen is now a major player in treating Traumatic Brain Injury (TBI), myocardial infarctions, and recently COVID-19.  

Well, that’s true for hospitals in China; China is also responsible for 95% of all publications on the clinical uses of Hydrogen. At the same time, China has embraced Hydrogen as a tool worthy enough for hospitals and medical schools to have Departments of Hydrogen Therapy. 

The publication “Beneficial biological effects and the underlying mechanisms of molecular Hydrogen – comprehensive review of 321 original articles” presents a review of 321 studies of molecular Hydrogen’s therapeutic uses, grouped by diseases or conditions.

Molecular Hydrogen Supplements

Making Hydrogen

Products that produce molecular Hydrogen are available through many retailers—most of the products producing Hydrogen saturated water fit in two categories – 1) tablets making Hydrogen saturated water or 2) electrical devices using electrolysis or similar techniques to produce Hydrogen. Of the two, tablets are easier to use, build a much higher concentration of Hydrogen, and therefore preferred. Pre-made Molecular Hydrogen water is sold packaged in various liquid containers. Packaged hydrogen water can be convenient, but currently, many have packaging problems. Some of the materials used in containers are too porous and leak Hydrogen. They have a short shelf life, and when tested, contain 0% Hydrogen.  

Is Hydrogen Safe?

 Hydrogen generation tablets produce Hydrogen saturated water by creating hydrogen nanobubbles that dissipate and ultimately dissolve in the water. Any Hydrogen gas escaping into the air would never reach the combustion threshold of 4%. 

Where do I find tablets? 

On the Farm, we use DrinkHRW’s product line. DrinkHRW’s products were developed by the team that did the first research in creating high-performance tablets, Alex Tarnava, and Dr. Richard Holland. DrinkHRW’s tablets are manufactured using high purity ingredients and uniquely certified to not contain substances banned by international sporting organizations. Most importantly, they spent months experimenting with nanoparticle sizes and reaction rates to produce a product that creates higher hydrogen levels. We, at the Farm, verified DrinkHRW’s hydrogen levels with tests of our own.

If you want to try hydrogen saturated water, We are able to provide you with 10% off your order today when you go to DrinkHRW and use code >> $CODE$ <<. A portion of your purchase will go to help support Fairy Dell Farms.  

Additional Resource  

 Molecular Hydrogen – Clinical Studies (G)

Publications providing an overview of research on the therapeutic use molecular Hydrogen for a wide range of conditions and diseases.

Molecular Hydrogen and COVID-19  (C)

Lists in-lab research, clinical trials, and clinical uses of molecular Hydrogen as a treatment for COVID-19.

Molecular Hydrogen and Sports (S)

Provides a sampling of the research on using molecular hydrogen by athletes. ( (Reducing recovery time from recovery, Improving O2 utilization and endurance, minimizing cerebral damage from mild TBI, and more)

DrinkHRW is the only tablet certified to not contain substances banned by international sporting organizations. Hydrogen water, produced using gaseous Hydrogen and using known water sources are also approved, As a sign of the approval of hydrogen water in athletic events, the Tokyo 2021 Olympics recently announced an ‘official’ hydrogen water vendor. 


Beneficial biological effects and the underlying mechanisms of molecular Hydrogen – comprehensive review of 321 original articles, Masatoshi Ichihara, Sayaka Sobue, Mikako Ito, Masafumi Ito, Masaaki Hirayama, and Kinji Ohno, Medical Gas Research, volume 5, Article number 12 (2015) 5:12 DOI 10.1186/s13618-015-0035-1