Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patient

S -T Wang,  C Bao,  Y He,  X Tian,  Y Yang,  T Zhang,  K -F XuQJM: An International Journal of Medicine, hcaa164, https://doi.org/10.1093/qjmed/hcaa164Published: 14 May 2020

Hydrogen, which exhibits anti-oxidative and anti-inflammation effects, was proved to be relatively safe for inhalation in diving.9,10 The concentration of hydrogen used in our study is quite lower (∼2.4%). Due to its small molecular weight, hydrogen can easily penetrate bio-membranes and diffuse into cytosol and organelles, and the tissue compatibility of hydrogen is stronger than many other oxidant scavengers. In this study, we demonstrated that a single inhalation of 45 min hydrogen gas could reduce airway inflammatory mediators in patients with asthma or COPD.


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